Gyrate Atrophy Details

Expanded Description

Gyrate Atrophy is a rare hereditary metabolism disorder primarily affecting the retina. The disorder is characterized by excessive levels of ornithine in the blood caused by a deficiency of mitochondrial ornithine aminotransferase.

Prevalence

150.0 ( Cases ) [Source]

Causes

Gyrate Atrophy is caused by a mutation of a gene found on chromosome 10. This gene is responsible for encoding an enzyme called ornithine ketoacid aminotransferase (OAT).

Disorder Symptoms

There are several symtpoms that affect patients with Gyrate Atrophy.

Name	Description
High levels of ornithine in the blood	High levels of ornithine in the blood
Tunner vision	Tunner vision
Night blindness	Night blindness
Myopia	Myopia
Progressive vision loss	Progressive vision loss
Posterior subcapsular cataracts	Posterior subcapsular cataracts
Muscle fiber abnormalities (type II)	Muscle fiber abnormalities (type II)
Reduced ornithine aminotransferase level	Reduced ornithine aminotransferase level
Blindness	Blindness

Diagnosis

No diagnosis information has been added yet.

Diagnostic Tests

No diagnostic test information has been added yet.

We don't have any tests yet.

Disorder Treatments

Low Protein Diet

We don't have any treatments yet.

Prognosis

No prognosis information has been added yet

Tips for Living with the Disorder

We don't have any tips yet.