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Malignant Osteopetrosis Details

Expanded Description

Normal bone growth is a balance between bone building and bone remodeling. Osteoblasts are cells that deposit minerals and osteoid to make bone. Osteoclasts remodel the mineral and osteoid to provide structure and strength for the bone while also building spaces for bone marrow to grow. Bone marrow is the red cellular material inside of bones that manufactures the cells in our blood.
X-rays of bones will show sclerotic or dense bones with minimal or no bone marrow space. Bones usually consist of a dense outer layer call the cortex, and an internal cavity made of a latticework of remodeled bone. Usually contained within this cavity is the bone marrow. In patients with osteopetrosis, this internal latticework may appear as dense as the cortex.

Please reference www.masonshafferfoundation.org

Prevalence

0.75 ( Per 100,000 Population ) [Source]

Causes

No causes have been added yet.

Disorder Symptoms

Mild forms of osteopetrosis can cause no symptoms.

People affected by severe osteopetrosis can display the following symptoms.

Name	Description
Deafness	Deafness
Facial paralysis	Facial paralysis
Blindness	Blindness
Increased likelihood of fractures	Increased likelihood of fractures
Stunted growth	Stunted growth

Diagnosis

No diagnosis information has been added yet.

Diagnostic Tests

No diagnostic test information has been added yet.

We don't have any tests yet.

Disorder Treatments

No treatment information has been added yet

We don't have any treatments yet.

Prognosis

No prognosis information has been added yet

Tips for Living with the Disorder

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