Ohdo Syndrome is a rare disorder characterized by learning disabilities associated with congenital heart disease, blepharophimosis (small eye openings), blepharoptosis (drooping eyelids), and small teeth.
Affected children are often very floppy at birth and have major feeding problems requiring tube feeding. They have generally decreased movements, particularly facial movements. Some, but not all, children have heart problems and some have an absent part of the brain called the corpus callosum (responsible for communication between the two halves of the brain). When the teeth erupt they are often very small. Many older children have had joint problems ranging from mild bending of a finger to more severe hip or spine disorders.
Progress in the first year of life is slow, and head control, sitting and walking occur late. However, ultimate progress is often better then was anticipated at first although all Children with Ohdo have significant learning disabilities.
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