Pemphigus Vulgaris Details

Expanded Description

Pemphigus Vulgaris is a rare autoimmune skin disease that causes blisters. Most cases can be controlled with treatment, which consists of steroid medicines and other medicines to suppress the immune system.

Prevalence

3.8 ( Per 100,000 Population ) [Source]

Causes

What causes pemphigus vulgaris?
PV is an auto-immune disease. The immune system normally makes antibodies to attack bacteria, viruses. and other ‘germs’. In people with auto-immune diseases, the immune system also makes antibodies against a part of the body. In people with PV, antibodies are made against a protein that binds the skin cells together. This antibody attack ‘dissolves’ the binding between some skin cells and causes the cells to separate from each other. Fluid builds up between the separated cells and forms blisters.

It is not known why PV and other auto-immune diseases occur. It is thought that something triggers the immune system to attack the body’s own tissues. Possible triggers include viruses, infection, or other environmental factors. There may be an inherited factor which makes some people more prone to develop auto-immune diseases.

Disorder Symptoms

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Diagnosis

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Diagnostic Tests

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Disorder Treatments

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Prognosis

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Tips for Living with the Disorder

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